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If the predictions are incorrect you throw out the theory.
The Matthews correlation coefficient is a convenient method for combining all of the predictions into a single value:
Here, we emphasize that the fact that at most 5.2% of the somatic rearrangement predictions are incorrect is the direct result of integrating data from all 129 tumor and normal genomes.
Because the structural, dynamic and functional aspects of these proteins have not been sufficiently characterized, it is difficult to tell whether these predictions are incorrect or represent plausible hypotheses awaiting better experimental verification.
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Critics were quick to write off skyscrapers immediately after the twin towers fell, but a year later it's clear such dire predictions were incorrect.
Only 6 predictions were incorrect.
Finally, there were three cases where our predictions were incorrect in both the full and epimastigote models: 1) malic enzyme, 2) pyruvate kinase, and 3) succinate – CoA ligase.
Finally, there were three examples in which our predictions were incorrect in both the full and epimastigote models: 1) malic enzyme, 2) pyruvate kinase, and 3) succinate – CoA ligase.
We also considered that additional cleavage sites could be preferred in the neighboring predicted site, or that the prediction was incorrect.
The induced phenotype change may represent adaptations that predict the future environment but that result in disease if the prediction is incorrect [ 7].
Since the prediction was incorrect this particular conspiracy was nipped in the bud.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com