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Predictions are further complicated by the presence of a number of vegetation types that change over time and also contribute to flow attenuation.
Our analytical predictions are further supported by numerical simulations for the two complex reaction schemes (Fig. 1bc).
We found that model predictions are further improved by the assured availability of the Health Department data.
Protein models generated by the searches and predictions are further searched against Markov model (HMM) databases, including PFAM [ 101], and automatically assigned a putative name based on domain hits or homology to previously identified proteins.
Regulatory predictions are further complicated by the fact that the cellular environment and stage of development affects the functional activity of regulatory elements - an element that is active in one cellular context may not be active in another, an aspect important to the study of disease.
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These predictions were further confirmed by the heterologous SNP analysis, which predicted the same aneuploidies, with the exception of chromosomes 20 and 23 from Sylvio, 7 from Esmeraldo and 6 and 14 from Arequipa that were predicted as tetrasomic.
The assessment of interface predictions is further complicated by the fact that proteins often have alternative interfaces with different partners, and that this should be properly accounted for in the computation of "true" statistics.
MicroRNA target gene predictions were further completed using the algorithms miRanda ([66], http://www.microrna.org/microrna/home.do), PicTar ([54] http://pictar.mdc-berlin.de/), and TargetScan 5.1 ([17] http://www.targetscan.org/).org/
These predictions were further tested for disease association using SNPnexus.
These predictions were further refined using TargetP v1.1 (Emanuelsson et al. 2000).
The results from in silico predictions were further validated with experimental evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com