We want the questions to encourage readers to examine evidence, note rhetorical and stylistic devices, investigate assumptions and claims, understand allusions, make predictions and consider context.
Predictions not labeled as 'REJECT' were accepted as confident somatic mutation predictions, and considered for subsequent downstream validation and analysis steps.
Additionally, they can incorporate expert interventions, produce explanations for alarm predictions and consider effects of medication on state changes to reduce false alert probability.
Logistic regression analysis was performed to examine the impact of age at diagnosis, tumor size and grade on the classification predictions and considered significant if the P-value was ≤0.05.
In case of TargetScanS the ratio was estimated to be 2.4 and 3.8 when considering all predictions and when considering only the positions conserved in all five genomes, respectively [ 11].
These molecules are also subjected for in silico toxicity prediction studies and considering their corresponding drug scores, it implied that, the molecules are promising as anticancer agents.
Heatwole and Rose (2013) used the magnitude of U.S. earthquakes as a hazard-related predictor variable for loss prediction, and considered the population of the affected area and GDP as exposure-related variables.
Therefore, we also associated a confidence measure with each prediction and considered restricting predictions to those instances where the associated confidence measure exceeds a given P-value cutoff, see the Supplementary data for details.
To determine putative mRNA targets for these candidates, we used six different computational target prediction tools and considered only targets that were predicted by at least two target prediction algorithms.
