It suggests that the therapeutic targets can be well identified in the top three predictions, and considering more targets ranked outside the top three would result in a significant number of false predictions.
Predictions not labeled as 'REJECT' were accepted as confident somatic mutation predictions, and considered for subsequent downstream validation and analysis steps.
Logistic regression analysis was performed to examine the impact of age at diagnosis, tumor size and grade on the classification predictions and considered significant if the P-value was ≤0.05.
Once the students have analyzed the pooled data, they must then interpret their results, comparing them with their predictions and considering them in the context of findings reported in the primary literature.
Researchers call this gap between your predicted reward and the reward you actually get the "reward-prediction error" and consider it an important teaching signal.
Heatwole and Rose (2013) used the magnitude of U.S. earthquakes as a hazard-related predictor variable for loss prediction, and considered the population of the affected area and GDP as exposure-related variables.
Therefore, we also associated a confidence measure with each prediction and considered restricting predictions to those instances where the associated confidence measure exceeds a given P-value cutoff, see the Supplementary data for details.
In case of TargetScanS the ratio was estimated to be 2.4 and 3.8 when considering all predictions and when considering only the positions conserved in all five genomes, respectively [ 11].
To determine putative mRNA targets for these candidates, we used six different computational target prediction tools and considered only targets that were predicted by at least two target prediction algorithms.
