Sentence examples for prediction threshold from inspiring English sources

By demonstrating in this study that three additional tripeptides are novel non-canonical PTS1 tripeptides, we show that novel tripeptides, even if positioned close to the prediction threshold, are correctly predicted as containing non-canonical PTS1 tripeptides.

As the TFBS prediction threshold increases, fewer TFBSs are predicted leading to less certainty about a gene's true operonic status.

Figure 4a shows that at a low TFBS prediction threshold (where more TFBS are predicted) it is more likely that sequences without a predicted TFBS are operonic (although only reaching a positive predictive value peak of ~0%).

One potential application to ML-based predistors is dynamically setting the prediction threshold such that the proportion of predicted active residues matches the estimated prior distribution for the query protein.

Indeed, only ~28% of genes predicted to be operonic are actually operonic at the highest TFBS prediction threshold.

To further assess the accuracy of the PWM models when the prediction threshold is varied, we have plotted them as receiver operator characteristic (ROC) curves (Figures 5,6).

To properly select prediction thresholds for the models, we experimentally evaluated affinity of 64 predicted FoxA BSs using EMSA that allows safely distinguishing sequences able to bind TF.

Based on these data, prediction thresholds can be set.

Since the effect would be an undesirable shift towards overprediction, a lowering of the prediction thresholds was rejected.

Calibration against experimentally determined structures suggests the use of three score classes with increasing confidence in the prediction, and prediction thresholds for each method.

When we changed the prediction thresholds to E-values <200 for HHpred and scores >5 for COACH, false positive rates more than quadrupled.