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The theoretical background of the prediction profile likelihood, also called predictive likelihood has been already studied [ 15].
In order to determine whether histological subtypes of cell lines and xenografts could be predicted as well with the 24-gene prediction profile, we applied this profile to two independent datasets.
A review of prediction profile likelihood approaches and a modification to sufficiency-based predictive likelihood is provided in [ 19].
Panel (b) shows, as an example, the prediction profile likelihood and the validation profile likelihood for this data realization for predicting A t) at time point t = 10.
Finally, the software generated a prediction profile photograph.
The analysis package calculated a prediction profile for each parameter, as shown in Figure 6.
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By repeating this procedure for continuous variations of the predicted value, the prediction profile-likelihood is obtained.
The JMP analysis performs an iterative optimization of parameters based upon the prediction profiles.
Ideally, pore pressure prediction practitioners will use both methods applied to several data types to compare prediction profiles.
Furthermore, prediction profiles can be created for no cross-flow cases by coupling material balance equation with layered backpressure equation.
The model is also capable of generating prediction profiles for every well in the production system in addition to forecasting individual layers production for each compartment.
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