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We tested the central prediction of the evolutionary theory of aging, that fast aging should evolve under conditions where selection late in life is weak.
Our results suggest that prediction of the evolutionary response to genome rearrangement is challenging, even in well-studied systems, but not without some success.
An important and robust prediction of the evolutionary model is that, although the overall prereproductive incidence of specific cancers is predicted to be independent of tissue size and turnover rate, postreproductive cancers will be most common in large rapidly dividing (typically epithelial) tissues (Nunney 2003).
The data from breeds of domestic dogs shown in Fig. 1, like the data from humans, are consistent with a critical prediction of the evolutionary model that an increase in size will increase cancer risk and hence result in selection for increased cancer suppression.
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The simulations verified predictions on the evolutionary profiles of the network based on our theoretical analysis.
Equipped with these tools, we may be able to make predictions on the evolutionary impact of current cultural factors.
Nonetheless, at least some human behaviour does seem to fit the predictions of the evolutionary theories reviewed above.
Now it is time to reinforce the powerful predictions of the evolutionary approach.
This experiment is a stringent test of both the assumptions and the predictions of the evolutionary theory of aging.
Given this and other inherent complicating factors, making accurate predictions of the evolutionary trajectories of salmonine fishes will be a difficult task.
It is therefore important to consider the multivariate feature of traits in an organism to provide more robust predictions of the evolutionary trajectory of populations as a result of novel selection pressures [ 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com