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cHPs are a heterogeneous collection of proteins that have proven very difficult to work with in the laboratory, or they have very complex domain combinations that hinder any prediction of functionality.
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When Categories were assigned, predictions of functionality were not taken into account.
Future research should research toward explicit models for divergence in intron exon structures among large sets of metazoans, to allow for systematic prediction of intron functionality across lineages and loci.
In cases where the taxonomy of the strains is well defined with reliable morphological features a prediction of the functionality of the FAEs cocktail present in each strain could be made possible.
The results for NucA provide some hints as to the sequence-based prediction of SP functionality, but the general conclusion is that such prediction is difficult.
Many previous studies have supported our prediction of compensatory functionalities of those two pathways.
Conclusions from this control experiment: CNS nondetectability or even total CNS loss is not correlated with gene death, so there is no need to modify the predictions of the functionality metric of table 1.
Prediction of gene function, performed as described in the Methods, provided inferred functionality for 1,229 of these protein-coding genes.
The list of model databases that also provide model development and/or prediction functionality includes OCHEM [8], Chembench [9], AMBIT2/OpenTox API [10] and GUSAR from the NIH [11].
Prediction functionality of EpiToolKit is completely provided by FRED.
As a preliminary prediction, the functionality of the motif associated with the Slr1037 response regulator will need more experimental proof.
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