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In the Japanese cohort, the level of positive prediction observed was lower (positive predictive value = 58%), while the biomarker identified Japanese nonresponders with a negative predictive value of almost 80%, which was the highest of any predictive value seen in this study.
Only the position and duration of the first break differs somewhat from the model prediction: observed breaks begin later and last longer than predicted by the model.
Seemingly, the gain in prediction observed is not driven solely by functional genic regions but by IGR as well.
Contrasting the cross-validated accuracies of prediction observed for tests sets with different degree of relatedness to the training sets clearly underlines that the precision to predict STB disease severity is mainly driven by relatedness.
Clinical effect under prediction observed in the results, which is more prominent in men in comparison to women is probably a consequence of the improperly coupled effects of the two tested drugs.
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In the model, Wd scales with σ2 and UNL with ε1.5NL, both predictions observed over a very large stress range.
While experimental kinematics and bone strains closely matched model predictions, observed pelvic fractures did not consistently agree with the model, and could not be solely explained by vehicle geometry.
Absent evidence, variations of an axiom were implemented and the consequences (in silico predictions) observed upon execution.
The few false-negative or false-positive predictions observed in the Dutch celiac population may also be explained by the presence of rare haplotypes.
There were no departures from Hardy-Weinberg predictiobservedrved in either the gDNA or wgaDNA genotype results.
Predictions observed in gene regulatory networks have been validated in small-scale experiments for individual transcription factors [ 29- 31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com