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In order to integrate the filtering results achieved in the binary subproblems, our proposal uses a soft voting approach considering a reliability level based on the aggregation of the noise degree prediction calculated for each binary classifier.
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For each mutant, SNAP returns three values (Fig. 1 A): the binary prediction (neutral/non-neutral), the RI (range 0 9) and the expected accuracy that estimates accuracy [Equation (1 )] on a large dataset at the given RI (i.e. accuracy of test set predictions calculated for each neutral and non-neutral RI; Fig. 1 C, Supplementary Online Material Fig. SOM_1 ).
This is the highest mortality reduction reported in any individual trial and even exceeds the most positive predictions calculated from meta-analyses for mixed populations.
The length of error bars is the confidence interval for the prediction calculated as: ŷi +/− 1.97* sŷ.
Use of a stochastic optimization algorithm, Tabu search, provided several carbohydrate excipient candidates with statistically similar property values, as indicated by prediction intervals calculated for each property.
Then, a prediction was calculated for CG variable for each respondent separately and according to the model.
However, the declining numbers fall well within the prediction intervals calculated for 2009 and 2010 (Fig. 4).
In the current study, the highest ROC-AUC's for MT prediction were calculated for hemoglobin, Quick value and aPTT.
The differences were not, however, statistically significant, probably because of the small number of prediction intervals calculated for each site.
Reliability of genomic prediction was calculated for the validation animals as the squared correlation between de-regressed proof and the EBV for the different traits.
These predictions were calculated for all models in the model library.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com