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This paper proposes an analogous model that relates a sequence to other sequences (i.e., the interaction of features) for predicting functionality.
This piece of work is a good example theoretically predicting functionality that can narrow down the search in the sequence space.
One future direction that yeast Ctf and, more broadly, CIN phenotypes will play a role is in predicting functionality for human CIN candidate genes mutated in tumors.
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Recently, we reported the characterization of three TRs of unknown function in which we used a manual version of our approach to predict functionality and identify potential effector metabolites [ 29, 38, 39].
The predicted functionality and performance are verified on an Energy-Recovery-Linac (ERL) electron accelerator.
Being able to predict functionality from knowledge of the structure, and explain how starch interacts with other major food constituents remain significant challenges in food science, nutrition, and for the starch industry generally.
SNPs with a predicted functionality score above 0.6 had a much higher success rate than those below 0.6 (χ2-test P-value of 0.0019), as found in Pavy et al. [23] for white and black spruce.
GWAVA aims to predict functionality of noncoding variants.
Thus, studies on predicted functionality were not conducted for this latter cDNA library.
For the androstenone-binding OR4D7, all 8 haplotypic alleles have similarly high degree of predicted functionality.
We then asked whether conserved binding in multiple mouse species could predict functionality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com