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In addition, with more and more genome-wide data being made publicly available (e.g., Gene Expression Omnibus) and ever-increasing numbers of computational approaches for predicting findings and hypotheses, examining figures reported in bioscience literature remains one of the most effective approaches for validating the predictions.
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In the present research, in vitro results confirmed predicted findings from our in silico work.
This complex formation was significantly enhanced in the presence of nuclear extracts from TNFα-treated cells indicating that TNFα increased the binding of these transcription factors to their binding elements that corroborates with our predicted findings detailed above.
The NRI represents the percentage change in predicted findings after including a new marker in the base model.
Study cases are carefully selected to pursue different patterns of theoretical replication; a larger number of cases (i.e., 6 10) provide more compelling support for predicted findings.
Detecting contamination is often very difficult before sequencing experiments, and it is only when results are markedly different from predicted findings that researchers may suspect contamination.
58, 59 Experimental validation is key to verifying that the predicted findings can translate into practice and also to improve current computational methods.
I-PET proved to be a superior diagnostic tool as compared to low-dose diagnostic I scans and adequately predicted findings on subsequent high-dose post-treatment I scans.
In this study, I-PET proved to be a superior diagnostic tool as compared to low-dose diagnostic I scans and adequately predicted findings on subsequent high-dose post-treatment I scans.
Although the length of the questionnaire did not pose difficulties during our pilot, future identification of a sub-set of questions, which predicts findings from the larger set, may be warranted.
The location of the debris means that the downed plane's location is consistent with the original search areas, where experts predicted finding debris from the crash over a year ago.
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