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Although MRP3 protein is predicted to integrate in the cell surface membrane, the precise membrane topology of MRP3 is complex and remains unclear.
Four of the Arabidopsis MMPs are predicted to integrate into the plasma membrane via a C-terminal hydrophobic helix, while the presence of an uncleavable signal peptide suggests the remaining family member resides in the ER lumen.
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Of 665 chromosomal sequences surveyed by prophinder [ 24], 358 (53.83%) were predicted to contain at least one integrated prophage, while the remaining 307 contained no predicted prophages.
Compared with SMART, MESSA has a broader incorporation of programs and the ability to predict three-dimensional structure, predict function and to integrate results from multiple predictors.
Because no single factor can accurately predict prognosis, statistical prediction models to integrate the cumulative effects of individual prognostic factors are required for more precise prognosis predictions.
Furthermore, DASMI is used by an iPfam client to integrate predicted domain domain interactions into iPfam results.
We employ the function FADE to integrate predicted residue contacts into the internal scoring function of Rosetta.
As the NCI-60 cell lines panel have been fully characterized by various "omics" technologies, the release of this drug combination matrix to the public could facilitate the development of novel computational methods to integrate, predict, and mine the interactions between molecular markers and drug combinations.
Thus, the suitability of PCM to predict COX inhibitor potency and to integrate multispecies bioactivity data opens new avenues for the design of cyclooxygenase inhibitors.
In health care, electronic health records have been vaunted as the best way to integrate care, predict the onset of disease, eliminate medical errors, and optimize follow-up care.
The purpose of this approach is not to predict the future, but rather to integrate knowledge of different components of the health care system into a single tool in order to a) promote understanding of how various factors affect the supply of and/or requirements for HRH, and b) identify policy levers for influencing each of these in Jamaica.
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