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In this process, we defined sdSNPs as "constantly consistent" when only one allele of sdSNP was predicted to be consistent with the GT-AG rule in every transcript.
The magnitude of intercorrelations between CDIP-58 subscale scores were predicted to be consistent with expectation about the proximity of the constructs, and were generally expected to be moderate in size (r = 0.30 0.70) [ 24].
When both alleles of a sdSNP were predicted (i.e., one allele was predicted to be consistent with the rule in some transcripts, but the other allele of the identical SNP was predicted to be inconsistent in other transcripts), the sdSNP was defined as "both cases".
The acquired DEX-resistance of ALL-27R was also strongly associated with gene networks under the control of MYC, MYCN and MAPK, with the direction of these changes predicted to be consistent with an activated status (a larger version of the network shown in Figure 2g can be found in Supplementary Figure 7).
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In addition, the transcriptional activity of both NFKB and CEBPB are predicted to be increased, consistent with their roles as central transcriptional mediators of the SASP.
A single putative copper ATP transporter was predicted to be anammoxosomal consistent with the anammoxosomal destination of some enzymes dependent on copper (or other metal cations).
This was noted in the Myc and TAG induced tumors where the Ras signature was predicted to be elevated, consistent with the large number of Ras activating mutations in these strains [ 15, 77].
The remaining KR domains have the tyrosine residue and the conserved motifs for NADPH binding (see Fig. S11 in the supplemental material) and are predicted to be active, consistent with the structure of the polyketide (Fig. 2).
Moreover, profile B harbored the highest set of genes (10.5%/37 genes) coding for proteins predicted to be secreted, which is consistent with the expected function of the secretome (Additional file 10).
Furthermore, the shortest O H length in crystals is predicted to be 0.806 Å which is consistent with the value of 0.798 Å detected by neutron diffraction measurements.
The majority of UV sequence changes were predicted to be neutral (174/254), which is consistent with the fact that a large proportion of UVs are expected to be benign [ 31].
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