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MAMDC1 is a poorly characterized gene spanning 835 kb of DNA sequence on the reverse strand of Chromosome 14q21.3, and predicted to be composed of two alternative first exons (1a and 1b) and 16 downstream exons giving rise to two mRNAs of similar size (5375 bp for isoform 1, and 5239 bp for isoform 2, respectively; Figure 3A).
The G/F domain is predicted to be composed of an α-helix and flanking loops.
Two fractions of the R125Q mutant protein were predicted to be composed of tetramers and octamers, respectively.
While the majority of FHA domains showed 6 beta-strands, Brassica rapa FHA was predicted to be composed of 4 consecutive beta-strands followed by an alpha helical region.
Interestingly, the time when AP-1 is most sensitive to these mechanisms is almost exactly the time in which AP-1 is predicted to be composed of equal parts ppc-Fos:ppc-Jun and ppc-Jun:ppc-Jun TF dimers.
The motif is 55% to 60% non-polar with a net negative charge, and is predicted to be composed of a series of alpha helices, producing a generally globular protein.
Similar(53)
Both sequences are located in a stretch that is predicted to be amphipathic and composed mostly of basic and hydrophobic residues.
From the knowledge of the first-extension behavior, the Mullins-type strain-softening is predicted and shown to be composed of two contributions: the strain-induced filler-cluster breakdown and the strain-induced increase in the network mesh size, which is consistent with the mechanism of entanglements removal at the matrix filler interface recently proposed and discussed by Hanson et al.
The computer model of human Puf-A predicted its structure to be composed of six Puf repeats, each of which constitutes a unique superhelix, half doughnut-shaped Puf domain (Fig. 2C).
SagE is composed of 220 residues and predicted to be a cytoplasmic membrane protein.
A second consensus cluster is composed of two soluble GTs predicted to be involved in 'protein translation' (LGG_00825-LGG_00826).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com