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Other cyclics such as S11 and S13 were predicted to be absent from the melt and they are known to be physically present in only trace amounts.
After removing contigs with fewer than 100 bp of contiguous unique sequence, 110,000 contigs spanning 29 Mb remained, which is close to the 25 Mb of euchromatic sequence predicted to be absent from the reference genome1.
A systematic workflow consisting of comparative genomics, metabolic pathways analysis and additional drug prioritization parameters identified 264 proteins of Vibrio cholerae which were predicted to be absent in Homo sapiens.
Within the broad putative current range of the python, the snakes are predicted to be absent from portions of the Thar desert in Pakistan, as well as the highest peaks in the Western Ghats of India.
We hypothesized that the phenotype observed in od10 homozygotes was likely due to a complete or severe loss of UEV-1 function, as half of the C-terminus of the protein is predicted to be absent.
This includes the presence of a polar residue at the ante penultimate position in the last four amino acids of the proteolysis tag (AKAA in H. pylori instead of AL/VAA, Fig. 4) and the absence of a SspB recognition motif, a proteolytic adaptor predicted to be absent in H. pylori.
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By using these mining tools, some genes predicted to be practically absent from normal tissues later showed expression in various normal tissues by RT PCR analyses (e.g. Myl5 and S100A7 Supplementary data, Figure 1A and B).
For 29 occluded traits 18 were strongly predicted to be present or absent, and the remaining 11 predictions were neutral.
Selected representative genes predicted to be present or absent by comparative genome hybridization (CGH) analysis were confirmed by gene-specific PCR (data not shown).
The in silico subtraction also resulted in the identification of 181 and 336 genes predicted to be present or absent in the tumor types compared to normal tissues, respectively.
On the other hand, the number identified could be underestimated, because the proportion of false P/A genes was predicted to be much lower when the absent frequency was higher.
More suggestions(15)
predicted to be pathogenic
predicted to be paramagnetic
predicted to be tight
predicted to be linear
predicted to be hsa-miR-9*
predicted to be severe
predicted to be non-druggable
predicted to be variable
predicted to be mobilization
predicted to be intolerant
predicted to be topological
predicted to be transmembrane
predicted to be obsolete
predicted to be modest
predicted to be recombinant
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