Sentence examples for predicted synergy from inspiring English sources

The outcome of the TIMMA model provides a list of predicted synergy scores for drug combinations, from which a target inhibition network can be inferred.

Our model thus predicted synergy between the drugs as arising from the heterogeneity of the underlying cell population and the resulting complementary activity of the drugs across cells.

The predicted synergy between APP and all its proteolytic fragments implies that the ratios of full length APP and all the various fragments, not just Aβ 1-40) and Aβ 1-42), are more important than absolute levels in coordinating neuronal responses.

The inability to predict synergy from genetic lesions is probably hampered by the necessity to restrict the analysis to recurring and highly focal copy number lesions as identified by GISTIC and the focus on the most frequent gene mutations in NSCLC.

The CMap approach also offers the possibility of predicting synergies of drug combinations.

Some of these researchers have defined tissue-specific enhancers by combining gene-expression profiling, genome comparison, and TFBS analyses [ 18] or have predicted TF synergy using the relative position and co-occurrence of TFBSs in the promoters of genes expressed only in a particular tissue [ 19].

Tyson predicted some synergies between the two companies, including the opportunity to produce some products in each other's plants and the ability to cut marketing costs by managing the entire meat category for big retailers.

The in vitro definition of synergy based on growth inhibition assays [ 9] does not necessarily predicts clinical synergy, because of drug metabolism or other factors.

DrugTarget-CDKO genetic interactions predict drug synergy.

Other studies have described measures for co-occurrence of pairs of motifs as a measure to predict TF synergy [ 19].

Given these previous experimental data, and the more realistic representation of in vivo processes by the +IM model, it is reasonable to speculate that the stronger synergy predicted by this model, rather than the weak/zero synergy predicted by the −IM model, is probably closer to the real drug combinatory effect one would see in patients.