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We find that epiallelic reversion, recombination, parent-of-origin effects, and transgressive segregation are key parameters in these populations: Their joint effects can produce complex and highly dynamic inheritance patterns that cannot be predicted from strictly Mendelian models.
The second and partially related problem is that the potential temporal instability of epigenetic variation can produce a level of phenotypic dynamics at the population-level that cannot be predicted from strictly Mendelian models of inheritance.
Such a lesion of their pattern-match model predicts strictly contralesional localization deficits, which is what is seen in all the animal lesion studies.
Being already known, the fact was not of course predicted in a strictly temporal sense, and yet, on Zahar's reading, it could have been: it was "use-novel" and thus fresh for use to confirm the theory.
Although these agricultural settlements in the hinterlands were not severely compromised as predicted by a strictly top down model of provisioning, health risks assumed by farmsteads may have resulted from provisioning to centers and/or corporate lineages while simultaneously mitigating larger risks (e.g., raiding).
More than 1,400 predicted genes matched strictly between D. stenobrocha and A. oligospora, indicating their close phylogenetic relationship.
Therefore, we considered that CNI of ACTN4 more strictly predicted the vascular invasion of cancer cells and poor prognosis than protein expression of actinin-4.
Since activation and repression can be mediated by distinct co-factors and binding sites [34], we concentrated strictly on targets predicted to be activated by the TF; these constitute the majority of the interactions in the reverse-engineered regulatory network and extension to repressed subsets is straightforward.
The strain GS-15 plasmid is 14 kbp, and encodes genes predicted to be involved strictly in plasmid maintenance [ 38].
While critical to examine structural changes prior to graft loss, predicting graft outcomes strictly based on the kidney biopsy is difficult and this invasive procedure has significant costs and risks for patients.
Recently, it has been reported that the amplification of ACTN4 can strictly predict the clinical outcome, and ACTN4 has been recognized as an oncogene 6, 11, 13.
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