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The ROC curve is a plot of true positives as a function of false positives based on various prediction score thresholds, where true positives are correctly predicted side effects and false positives are incorrectly predicted side effects.
It is found that allowing aeroelastic coupling significantly affects the response of the nozzle and the predicted side loads.
The predicted side effect was confirmed from the literature (Horowitz et al., 2005).
The fourth ranked predicted side effect is 'tremor' for Bepridil (DB01244), an antihypertensive drug.
TWOSIDES [ 18] is a database that contains predicted side effects associated with pairs of drugs.
Some of the top-ranked predicted side effects involve Cinnarizine (DB00568), an anti-histaminic drug used against motion sickness.
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The fixed-backbone model performs reasonably well with an overall rmsd between computed and predicted side-chain order parameters of 0.26.
It is true that, if I advise someone "Get drunk", he might respond "Are you telling me to have a hangover?" Yet this inference is not acceptable as leading from one intention to another; for predicted side-effects of realizing one's intentions are not thereby intended, even if (in another case) they are welcome.
To address this, we compared the predicted side-chain structures given the native backbone structures and those given the predicted backbone structures in terms of free energy.
We used the data from Figures 3 and 4 to model the hind paw alternation and calculated the predicted side-to-side tail trajectories across walking speeds.
Predicting side effects of drugs is a critical issue for the drug discovery.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com