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Figure 8 presents the pooled and predicted sensitivity and specificity estimates together with the credible and prediction regions for this analysis.
Figure 6 presents the pooled and predicted sensitivity and specificity estimates together with the credible and prediction regions for Xpert for TB detection.
The Basal-like subtype is also enriched for tumors predicted to be sensitive to doxorubicin, and a complementary pattern was found with predicted sensitivity to topotecan, suggesting additional opportunities for combination therapies that might be effective in this subtype.
The rapamycin response signature predicted sensitivity for 94% of basal-like breast cancers in a large dataset.
The calibration results that verified the theoretically predicted sensitivity are also presented along with a brief description of the improvements being currently implemented to increase this sensitivity level by approximately 20 dB.
The polyp-detection algorithm is statistically trained on low-dose virtual colonoscopy data from 13 patients with a predicted sensitivity of 92% and a false-positive rate of 9 objects per study.
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The ROC curves were in this study generated to compare the AUCs and the predicted sensitivities and specificities among different NETs and different stages of disease.
These results fit well with the predicted sensitivities to amino acid starvation of the isoacceptor tRNAs that recognize these codons [36].
The predicted rapamycin sensitivity differed between subtypes, with the more aggressive subtypes - such as basal-like, HER2-overexpressing and luminal B - having much more frequently predicted sensitivities.
An additional opportunity afforded by the availability of signatures predicting sensitivity for multiple cytotoxic agents, as well as pathway activation, is the identification of potential combinatorial strategies that would derive from overlaps in the predicted sensitivities.
Veeck, J. et al. BRCA1 CpG island hypermethylation predicts sensitivity to poly adenosine diphosphate -ribose polymerase inhibitors.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com