I concern regarding the predictive power of TFSVM methodology, performance of the method, biological significance of predicted targets, interpretation and extrapolation of the results, and independent validation.
49 Several analyses of NNRTI resistance patterns in clinical routine samples demonstrate that currently resistance to etravirine, as predicted by interpretation algorithms, is rare.
On the basis of the morning rehearsal, Mr. Horowitz predicted a dark interpretation, heavily tinged (or untinged) by shadows of war.
Due to the absence of a linear correlation between the score and the correct taxonomic level of the predicted assignment, this interpretation is infeasible.
*For ease of interpretation, predicted measurements at various ages are shown in addition to the rate of growth in ln kg or cm)/ln(months).
This annotation of PPIs resulted in: (i) identifying more evidence for curated PPIs and providing more biological context for them, and (ii) providing some level of validation for PPIs detected by high-throughput methods and predicted computationally (human interpretation and curation of extracted evidence is still required).
Because experts have a clear conceptual model of basic chromosome structure, they do not view textbook drawings and diagrams in the same way students do and cannot even predict the interpretations that students will make looking at the same picture (Benson, 1997).
The probability of liquefaction volumes compare well with those predicted using geologic interpretations.
The downside of this result was that for those cases, we no longer have evidence as to which flavor of disorder is predicted; this makes interpretations about the structural and functional impacts of the region more challenging.
These algorithms use a three- or four-level category classification of predicted resistance, with interpretations such as 'high-level resistance'intermediateate resistant', 'possible resistance', or 'recommended drug to be used for treatment', among others.
Each drug-specific document includes a description and mechanism of action of the drug, summary of the key publications supporting the PGx evidence, and the PhAESIS evidence scoring of key genetic variants, drug-specific genotype-phenotype correlations and predicted drug response interpretations.
