Exact(29)
In mammals, predictions are ranked based on the predicted efficacy of targeting as calculated using the context scores of the sites.
Targetscan predictions in vertebrates are ranked on the predicted efficacy of targeting as calculated using the context + scores of the binding sites, which takes into account the type of seed pairing site, miRNA-target complementarity outside the seed region., local AU content, site position within 3'UTR, target site abundance, and seed pairing stability [ 20, 90, 91].
(c) was the comparison between predicted efficacy and experimental inhibition.
Fig. 2 Structures of 5 active compounds Fig. 3 The linear fitting between predicted efficacy and in vitro experimental results.
Quantitative imaging in this pre-clinical model has proven to be a useful tool in evaluating both the targeting and residence of radioimmunotherapy agents and thus their predicted efficacy while still in a pre-clinical phase.
Bridging the fields of basic immunology and vaccine research is needed to create individualized host immune profiles that will direct the rational development of customized adjuvants and vaccines with a predicted efficacy in each target population.
Similar(31)
However, because the frequency of the double dhps mutation alone is low, this uncertainty has little impact on the predicted efficacies for each site.
Therapeutic studies using transgenic rodent models often fail to predict efficacy and outcome in human patients.
Combination analgesics are effective in acute pain, and a theoretical framework predicts efficacy for combinations.
In general, animal models have failed to predict efficacy of medications developed for visceral pain.
Perhaps PRS analysis can also be used to predict efficacy of the Calcitonin Gene-Related Peptide (CGRP) monoclonal antibodies that soon become available, presumably at a high cost.
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