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There were no other factors at baseline that predicted benefit from training.
We explored whether expression of the hypoxia marker hypoxia-inducible factor-1 α (HIF-1 α) alone or in combination with other markers predicted benefit from CON.
A reanalysis of the MTOPs trial suggested that prostate size (as measured by volume >25 mL) predicted benefit from combination therapy.
In 13 cases, patients had high or intermediate prognostic risk, but no predicted benefit from extended endocrine therapy (Supplementary Table 1).
Prospective validation of the predicted benefit from chemotherapy in the higher RS patients is taking place in the TAILORx trial (Zujewski and Kamin, 2008).
In support, we showed previously that tumour necrosis is an independent prognostic factor in invasive bladder cancer, and both necrosis and expression of the hypoxia-inducible enzyme carbonic anhydrase IX (CAIX) predicted benefit from hypoxia modification (Eustace et al, 2013a).
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For example, in silico modelling has predicted benefits from the elevation of creatine in combination with total adenine nucleotides and total exchangeable phosphate pools.
In addition to having a prognostic impact in breast cancer, uPA and PAI-1 measurements in breast cancer appear to possess therapy predictive value, especially in predicting benefit from cyclophosphamide-methotrexate-5-fluorouracil (CMF) in the adjuvant setting.
Furthermore, evidence is lacking on the ability of VEGF family members to predict benefit from specific treatments, especially on their predictive value for bevacizumab use.
Thus, it is important to identify factors among the older population that predict benefit from ICU treatment, establish prognostic factors for long-term survival, and elucidate the HRQOL.
Mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene predict benefit from tyrosine kinase inhibitors in patients suffering from non-small-cell lung cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com