Our model predicts a requirement for bi-directional, or diffusion-like transport to generate realistic patterns, and suggests that not only the direction, but also the rate of transport has a significant impact on branch patterning.
The distance predicts a requirement for a 10-residue spacer between the PPXY motif that binds the WW3 domain and the acceptor lysine that receives Ub from the HECT cysteine.
This is the most significant variable for predicting a requirement for targeted treatment of myocardial iron overload and it cannot be replaced by serum ferritin, liver iron or any other measurement.
The rescue data predicts a stronger requirement for the GLS in the localization of transcripts to the oocyte's AD corner.
These observations reveal a heterogeneous requirement for Wnt/β-catenin signaling among ECs during brain invasion in zebrafish, and they predict a similar differential requirement between tip and stalk cells in the mammalian brain and retina.
We predict a lower G2/M requirement for Cdc28p (and likewise Hsl1p and Clb2p) in a background with lower than WT Swe1p levels.
Celi's group reports that Bayesian theory can predict a patient's fluid requirement on day 2 in 78% of cases, based on data collected on day 1 and the known associations between those data, based on observations in previous patients in their unit.
The increased transcript levels of genes involved in PAT, DAT, and sulpholipid synthesis in H37Rv, as seen in our study comparing intracellular H37Ra and H37Rv, are predicted to be a requirement for remodeling of the bacterial cell envelope upon internalization [40].
12 The necessity of a general base in HNL catalysis has been proposed more than 45 years ago by Becker and Pfeil, 13 who also predicted the requirement for a positive charge in the active sites of HNLs to stabilize the negative charge evolving at the cyano group during the reaction.
The above data support a predicted requirement for GluN2B-mediated signaling in the actions of ketamine, yet an important question remains, how does a non-selective NMDAR antagonist like ketamine produce a seemingly selective effect on GluN2B-mediated signaling?
