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Dynamic exposure has been shown to reproduce a more predictable dose compared to static conditions75.
The rats that pressed one lever learned that they would always get a predictable dose of sugary water.
This is probably safe, but a cut patch may not provide a predictable dose, said Dr. Michael C. Fiore, director of the tobacco research and intervention center at the University of Wisconsin Medical School.
Gevokizumab showed predictable dose linearity with maximum concentrations proportional through the observed dose range.
Although the toxicity of irinotecan or an EGFR inhibitor is predictable, dose adjustment should be made when necessary.
The granisetron TD patch uses a drug-in-adhesive matrix diffusion method to deliver a predictable dose of granisetron for up to 7 days.
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This study shows that AMD473 is devoid of significant organ-specific toxicity, and has predictable, dose-limiting myelosuppression and linear pharmacokinetics, as predicted by preclinical studies.
Data from phase I trials show that bortezomib induces predictable, dose-related, reversible inhibition of proteasome activity.
These shorter chains reduce binding affinity for plasma proteins and cells, resulting in a longer half-life and more predictable dose-response.
He was trailed by a sizable legion but received only the predictable doses of "You're the man!" exclamations and general good wishes.
However, these effects, due to the molecule pharmacology, are predictable, dose-dependent, and no clinical consequences were reported.
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CEO of Professional Science Editing for Scientists @ prosciediting.com