Exact(3)
The combination of simulation methods allows us to predict the pathway taken by the amino acid, which is enabled by conformational rearrangements of the extracellular loops of the protein.
Despite the fact that FBA has the ability to predict the pathway cross-talks, it does have limitations.
All of the wild goat genes were aligned against KEGG [ 22] proteins using Blastp to predict the pathway in which the genes might be involved.
Similar(57)
The Pathologic module was used to predict the pathways for both the genomes.
How to predict the pathways computationally is a challenging important question in the post-genomic era.
The results suggest that our method can predict the pathways without the prior information about the pathway structure and pathway length.
More recently, Lee et al. [26] proposed a method that predicts the pathway activity using only a subset of genes in the pathway, called the condition-responsive genes (CORGs), whose combined expression levels can accurately discriminate the phenotypes of interest.
Pathway tools software [ 51] was used to predict the metabolic pathway for F. noatunensis subsp. orientalis.
A first attempt to predict the periplasmic pathway pulled artificially a lactose molecule through a LacY structure, which was sealed towards the periplasm23.
A bond-valence energy landscape calculation is used to predict the conduction pathways of lithium ions.
Given that domino reactions proceed without the isolation of any intermediates, judicious planning is required to predict the reaction pathways by combination of known transformations.
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