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The characterization of a deleterious splicing variant is a complex task that requires a functional validation as bioinformatics predictions are not today able to predict the consequence of a splicing motif alteration at the mRNA level.
Network analysis of the expression data was used to predict the consequence of each transfection on cellular function and these predictions were experimentally tested.
This competition between exogenous and endogenous sequence complicates the analysis of possible gene editing outcomes make it difficult to predict the consequence of gene editing.
To better predict the consequence of landslides, a robust computational tool that can capture the whole process would offer additional information of significance.
We next evaluated whether the simple formalization as a dynamical system of the known qualitative gene regulatory relationships can predict the consequence of gene knock-out experiments [35].
These data demonstrate that spatial models are needed to accurately predict the consequence of membrane heterogeneity on signal propagation and set the stage for more refined considerations of signaling platforms.
Similar(52)
Consequently, detailed studies of selection and demographics will be necessary to predict the consequences of species interactions in changing environments for any particular ecological community.
Trying to predict the consequences is a major challenge.
It is difficult to predict the consequences of such a move, however.
So did her friend, who said: "We can't predict the consequences of anything.
No analyst can predict the consequences of the jihadist involvement in the fighting, but its influence is growing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com