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We have modeled four degrees of freedom to predict positions of hydrogen atoms in protein structures: Two different tautomeric states can be observed for histidine residues.
In some, he asks for her advice on the design of scientific instruments, such as a hydroscope (used to determine density of fluids) and an astrolabe (used to predict positions of planets).
We also propose a new approach to predict positions with functional specificity based on the reconstruction of ancestral sequences.
- The histone code hypothesis gradually transformed into the histone context hypothesis,, as several different modifications should be considered simultaneously to predict positions of genome regulatory elements - and to determine the type of chromatin domain (reviewed in refs. 54 and 55).
We show that the usage of hypothetical ancestors together with the present day sequences improves profile-based sequence similarity searches; and that ancestral sequence reconstruction methods can be used to predict positions with functional specificity.
Because the only way to predict positions where substitutions will become fixed is to predict their effect on fitness, sites that are predicted to remain conserved with high probability are likely to be functional ones.
Similar(54)
The original formulation of the population vector method predicted velocity and did not predict position directly.
A part of this challenge was to predict position weight matrices (PWMs) that describe the specificity profiles of five PDZ domains to their target peptides.
Ellipses represent the uncertainty on the predicted positions (based on [[9]]).
Their exact or predicted positions on the 26S proteasome complex can be seen in Fig. 1.
The control strategy takes other vehicles predicted positions into account for cooperation purpose.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com