Sentence examples for predetermined expression from inspiring English sources

To better illustrate and map co-regulated genes with different activation and deactivation profiles, the levels of every transcript have been assigned to graphs of "Expression Waves" that follow a particular, predetermined, expression pattern (Figure 5).

Here, CRMs were evolved in silico to drive predetermined expression patterns along the A/ P axis.

The generation of further Ad5 complementing cell lines from any of the LoxP parent cell lines isolated here should be facilitated as the cell lines obtained will have predetermined expression properties.

We used the PEBCRES simulation framework (He et al. 2012; Duque et al. 2014) (fig. 1 A and B) to evolve sequences that drive a predetermined expression pattern, simulating the process of evolutionary adaptation under a variety of scenarios.

We did not include predetermined fold expression filters in the analysis because the biological implications of a specific threshold change in gene expression are not clear.

Cell differentiation is traditionally seen as a sequence of genetically predetermined gene expression changes.

We did not include predetermined fold expression filters in the analysis, because the biological implications of a specific threshold change in our target gene set have not previously been established.

The first of these, the PatternRecogniser, uses predetermined regular-expression style heuristics while the second, the MEMMRecogniser [19], employs machine learning in the form of a Maximum Entropy Markov Model (MEMM).

In order to improve our ability to conduct epi-allelic analysis, we developed a robust flow cytometry-based functional screening approach to enable unbiased selection of shRNAs that generate graded knockdown of target gene expression to predetermined levels.

These results demonstrate that flow cytometric selection of RNAi knockdown cells combined with deep sequence analysis can be used to identify multiple shRNA sequences that reduce target gene expression to predetermined levels.

In order to improve our ability to incorporate epi-allelic analysis into target validation studies, we developed a novel flow cytometry-based functional screening approach (CellSelectRNAi) to achieve unbiased selection of shRNAs from high-coverage libraries that knockdown target gene expression to predetermined levels.