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The predetermined definition of postoperative pharyngolaryngeal morbidity for assessment: sore throat was defined as "constant pain or discomfort in the throat independent of swallowing"; dysphagia was defined as "difficulty or pain provoked by swallowing"; dysphonia was defined as "difficulty or pain on speaking"[ 10].
Each study was assessed in an unblinded fashion [ 13] and was evaluated for the adequacy of allocation concealment, the blinding of the diagnosis of pneumonia, the production of an intention to treat analysis and the presence of a predetermined definition of pneumonia.
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Studies using these predetermined definitions of periodontal disease did not find a clear linear relation with type 2 diabetes and prediabetes (6, 11).
13 17 22 24 Thirdly, where the interpretation of previous reviews was hampered by pooling of data based on variously defined exacerbations, we applied predetermined standardised definitions based on those of the American Thoracic Society/European Respiratory Society.
The 40% was predetermined as the "definition" of positive before the study was done based on our previous analyses in acute myeloid leukemia demonstrating a natural clustering of data above and below 40% (Gibson SE, et al. USCAP Meeting Poster 151, March 2007).
The nationwide inpatient sample database predetermined the category definitions.
The predetermined subgroups were based on asthma definition, the age of offspring, and study design.
16 Where studies did not use the Lake Louise scoring system, we chose the primary end point to be the absence of acute mountain sickness, defined using a validated symptom scoring system such as the general high altitude questionnaire, the acute mountain sickness-cerebral score, or a clear definition of acute mountain sickness predetermined by the original study authors.
This definition was adopted based on our predetermined 'minimal clinically important difference' (MCID) of FACT-Cog in our cancer patients [ 9].
We either generated 5 random locations per use location or 10,000 random locations (total) within 4 predetermined areas around use locations to determine how the definition of availability and the number of random locations affected results.
Given the initial mRNA state (which is usually an empty mRNA, i.e., x i = 0, i ∈ I c ), the rate law (1) with the predetermined update rule defines completely the ribosome dynamics in Figure 1, thus yielding a complete definition of the codon-based (stochastic) model for mRNA translation.
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