Sentence examples for predefined margin from inspiring English sources

This predefined margin is considered appropriate from a clinical perspective because of the broad therapeutic window and high variability of INX.

Including LD-rescue data, the adjusted mean decrease was −8.5 versus −9.4, revealing a difference of −0.9 (95% CI: −2.7, +0.9), which is still well within the predefined margin.

If the ratio of this improvement over current lifetime T h is smaller than a predefined margin H, e.g., T h - T h - 1 T h < H, a counter CT is increased by 1; otherwise, it is reset to 0. When CT > TH, the whole CG procedure is terminated.

For this study, the predefined margin of non inferiority was defined as a hazard ratio (UDT plus Cycloset® versus UDT plus placebo) of 1.5.

16 After 48 weeks of treatment, this study showed a noninferiority of once-daily NVP-XR 400 mg compared with twice-daily NVP-IR, for a predefined margin of −10%.

The primary analysis tested the hypothesis that the occurrence of all-cause serious adverse events for Usual Diabetes Therapy (UDT) plus Cycloset™ is not inferior to that for UDT plus placebo by a predefined margin.

These values were within the predefined margins for equivalence (80 125%), thereby satisfying the criteria set for PK equivalence of CT-P13 to INX.

Thus, the upper limit of the 95% CI met the predefined noninferiority margin of 0.4%.

Biosimilar was noninferior to the reference, because the lower bound of the 97.5% CI was entirely above the predefined noninferiority margin of −1 day.

However, presepsin was not able to differentiate septic shock at day 3 (AUC = 0.72; that is, <0.75 predefined AUC margin), whereas the AUC of IL-6 was 0.76 at day 3.

Whenever appropriate, the 90 % confidence intervals (90 % CI) were compared to predefined equivalence margins.