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Furthermore, the number of epitope precursors that bind to 1, 2 or 3 MHC molecules is underrepresented, whereas the number of epitope precursors that bind to 4 or more MHC molecules is over-represented in HIV-1.
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V3C18 (Mr = 170 kD) was proteolytically processed into a cell surface FZC18-containing 50 kD glycoprotein precursor that bound Wnt3a in vitro through FZC18 and suppressed Wnt3a-induced stabilization of β−catenin.
We hypothesize that formation of the specific GBP-glycan complex is also preceded by weakly bound precursors that are sensitive to the local physicochemical environment on the cell membrane surface.
LAP is the N-terminal propeptide of the TGF- β precursor that noncovalently binds to TGF- β, forming a latent TGF- β complex and favoring the release of TGF- β into the extracellular milieu.
On the other hand, if miR-519 is regulated post-transcriptionally, identifying RNA-binding proteins that bind to the miR-519 precursor transcripts would provide insight into the regulation of miR-519 abundance.
There are three well known monolignol precursors that polymerize to form the lignin that binds plant cell walls together: p-coumaryl alcohol, coniferyl alcohol, and sinapyl alcohol.
The last step in DAF-12 ligand biosynthesis is catalyzed by a cytochrome p450 called DAF-9, which converts inactive precursor steroids into the active ligands that bind to DAF-12, thereby promoting reproductive development (Gerisch et al., Dev Cell; 2001).
To reach the triacylglycerol production lower bound, the HM converts some of its glucose to triacylglycerol precursors that are then transported to the AM, very similar to what occurs physiologically [ 20].
Q14439_Hum branch off orexin receptors that bind to two novel neuropeptides, orexin-A and B, derived from a common prepro-orexin precursor by proteolytic processing [ 36].
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