Sentence examples for precursor microRNA from inspiring English sources
Heo, I. et al. Lin28 mediates the terminal uridylation of let-7 precursor microRNA.
Double-stranded RNA endoribonuclease that cleaves long or hairpin double-stranded RNA into small interfering RNA or precursor microRNA into microRNA.
After two-step cleavages by Dicer-like 1 (DCL1), the pri-miRNA is processed into the pre-miRNA (precursor microRNA), then into a miRNA/miRNA* duplex.
The regulation of microRNA biogenesis consists of three major steps 1) pri-miRNA transcribed by RNA polymerase II and III; 2) microRNA maturation, including nuclear cleavage of the pri-miRNA to precursor microRNA and nucleocytoplasmic export, and 3) RISC (RNA-induced silencing complex) assembly that converts pre-miRNAs to mature microRNAs [11], [12], [13], [14].
SNP rs2910164 is a sequence polymorphism in the precursor microRNA (mir 146a.
To date, several hundred precursor microRNAs (pre-microRNAs) and mature microRNAs have been annotated in several mammalian genomes [3].
Chak, K., Roy-Chaudhuri, B., Kim, H. K., Kemp, K. C., Porter, B. E., Kay, M. A. Increased precursor microRNA-21 following status epilepticus can compete with mature microRNA-21 to alter translation.
Thus, precursor microRNAs may have hitherto undetected novel functions in nuclear gene expression.
ADAR-mediated RNA editing of the double-stranded portion of primary and precursor microRNAs were shown to result in the redirection of the silencing target of microRNA (Blow et al., 2006; Das and Carmichael, 2007; Kawahara et al., 2007b).
Thousands of precursor microRNAs are precisely processed into microRNAs with a typical length of 20 25 nt by RNase III enzyme Dicer (Griffiths-Jones et al., 2008; Schraml and Grillari, 2012).
