Exact(1)
Our ability to engineer de novo a functional minimal miRNA precursor highlights that we have discovered several elements both necessary and sufficient for accurate miRNA processing.
Similar(59)
The high level of Fyn in thymic precursors highlights the importance of Fyn activity during an early stage of T cell development.
Clonal labeling of early cardiac precursors highlights the heterogeneity among Mesp1+ progenitors, including the existence of precursors that are restricted in their anatomical contribution, especially to distinct ventricular chambers.
The recent and major discovery of the role played by post-transcriptional modifications of miRNA precursors highlighted the complexity of miRNA biogenesis and the way miRNAs act [ 30, 31].
We gathered sequence data from these transgenes and used it to build a MIR172a precursor map highlighting relevant and neutral positions for its processing.
The folding structures of the new miRNA precursors identified were obtained with the UEA sRNA toolkit-RNA hairpin folding and annotation tool, which uses the Vienna Package to obtain the secondary structure of a precursor sequence, highlighting the miRNA/miRNA* sequences on the hairpin structure.
This work proves that the mechanical response of recycled composites can rival that of virgin precursors, while highlighting the benefits of application-driven optimisation of reclamation processes.
The constituents of the ceramic precursors are highlighted in Table 1 (see Fig. 1).
*The cyclotides precursors are highlighted.
In Figure 2, miRNA mature sequences and miRNA* sequences in miRNA precursors are highlighted using different colors.
Our analysis demonstrates that oysters possess conserved molluscan neuropeptide domains and overall precursor organization whilst highlighting many previously unrecognized bivalve idiosyncrasies.
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