Findings with respect to accuracy indicated that instructions to imagine the patient's perspective helped to prompt adjustments down from a self-oriented viewpoint, although definitive conclusions were precluded by difficulties with order effects.
However, confirmatory biochemical IC50 determinations were precluded by difficulties in expression of catalytically active TbAUK1.
Measurements by means of patient questionnaires and proxy assessments will be carried out at baseline, after 3 and 6 months It is expected that some patients will develop either cognitive problems or other difficulties precluding that they fill out the questionnaires adequately during the study.
Previously, investigation of immortal DNA strand function and molecular mechanisms responsible for their nonrandom co-segregation was precluded by difficulty in identifying DSCs and immortal DNA strands.
The fact that almost half of the children were diagnosed with a possible bacterial infection indicates the difficulty of precluding this diagnosis.
The difficulty of precluding metal binding, even in the presence of strong chelating agents, has also been observed previously in studies of the proteins PsaA from S. pneumoniae [ 40] and MntC from S. aureus [ 21].
Experimental difficulties preclude the direct measurement of these tensors.
When a participant perceived a visual object, they were asked to point to its location on the screen or, alternatively (if their movement difficulties precluded this), state which quadrant of the screen they saw the object.
It would have been preferable to have involved students from each college in undertaking the audits because it is they who are familiar with their surroundings, but this was precluded by the difficulties of gaining permission to involve them and to train them in procedures.
While these studies are important for biomarker discovery, several difficulties preclude their translation into a clincial setting.
Although all yields were within one order of magnitude of each other these yields should be regarded as semi-quantitative since technical difficulties precluded accurate estimation of the biofilm biomass in individual cultures.
