Nonetheless, a small proportion of neurones (< 1%) expresses both viral antigen and LATs during acute infection (Margolis et al., 1992; Speck & Simmons, 1992) raising the possibility that expression of lytic cycle genes may not preclude entry into latency.
Thus, high aspirin usage precluded entry to many patients, often those at the highest risk of AVF access failure, thereby potentially diluting the trial's ability to detect a true benefit of omega-3 PUFAs and aspirin.
These challenges may not preclude entry, but they should certainly be considered before entertaining this kind of market expansion.
At a time when the integrity of professional sports has been eroded by all manner of misdeeds by participants, one would think that caretakers of the sport would make it clear that certain trespasses would automatically preclude entry into a Hall of Fame.
As the structure of GdPC precludes entry into cells, potential cytotoxicity was assessed by stimulating CCT activity using linoleate in KPC cells in vitro, leading to increased GdPC concentration and synergistic growth inhibition after dFdC addition.
While the narrow barrel of the proteasome precludes entry of protein aggregates and organelles,, such substrates can be degraded by macroautophagy, hereafter named autophagy., Autophagy involves the formation of double-membrane structures called autophagosomes, which fuse with lysosomes to form autolysosomes where the autophagosome content is degraded by proteases and acidic pH.
Were the old deemed to have a constitutional right to preclude the entry of the new into the markets of the old, economic progress might grind to a halt.
Whilst government participation in the provision of support services is necessary in certain areas to safeguard the public, care must be taken to ensure that government services do not preclude the entry of the co-operative and private sectors.
The low extracellular pH of most tumors precluding the entry of a number of weakly basic drugs such as doxorubicin, conferring drug resistance, can now be overcome.
The catalytic triad residues Ser-His-Asp (S111, H136, D185) are enclosed in a single cavity that allows for degradation of small peptides but precludes the entry of the large folded polypeptides [ 16, 57, 58].
