In parameter estimation, the principle issues are the precision of the estimates and the practical reality of the computational burden.
In such cases, model based small area estimation techniques can be considered to improve the precision of the estimates.
Since aggregating the data reduces the number of observations substantially, the precision of the estimates decreases.
It also highlighted other methods that produced satisfactory statements of the precision of the estimates.
Sample-size requirement depends on the prevalence of the disorder and the precision of the estimates needed.
Given the large population size, this did not induce an excessive loss in precision of the estimates.
The results obtained are convincing, because of both the precision of the estimates and the simplicity of the implementation.
20Notice that the small sample size for certain type of transitions could affect the precision of the estimates.
In this situation the experiments should be replicated in order to improve the precision of the estimates.
When performed appropriately, meta-analysis may enhance the precision of the estimates of the effects of risk alleles, leading to reduced probability of false negative results.
On the other hand, estimates of the secondary attack rate from older persons to older persons increase, while the precision of the estimates decreases.
