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Very low E-values can be based on partial matches, and thus do not correspond precisely to sequence similarity.
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The second way the operon map has evolved is related to local sequence evolution, and more precisely to intergenic sequence evolution.
The regions that mediate these interactions and their respective secondary structures were mapped precisely to the p53 sequence.
Filtering size should be chosen precisely to get correct target sequences from the environmental sample after removing large cells or debris.
An additional benefit of using a synthetic peptide cross-linker to form our hydrogel network is that we are able to dictate precisely its sequence to include a variety of biological functionalities, as well as to include non-natural amino acids that enable additional modification of the system postgelation independent of the network mechanics.
The type of sequencing errors and their rate is inherent to the sequencing technology and more precisely to the nucleotide elongation detection methods used.
To precisely sequence the long tandem repeats, a series of deleted subclones was made from the resultant subclones using the Exonuclease III deletion method [ 54].
Unfortunately, using standard mapping techniques, it is close to impossible to precisely map DNA sequences to interbands as their axial lengths are quite small (0.12 mkm on average) [ 2].
From the clinical point of view, an ideal technology for detecting EGFR multi-mutations should achieve the following: (1) accurate enough to precisely provide sequence information about specific kinds of mutations; (2) simple and cost-effective to be accepted as a routine test before cancer targeted therapy.
We used lastz program and lastz-based Cassis program [ 56] to precisely detect sequence homology and genomic rearrangement breakpoints.
To precisely capture the sequence context of these SVs, we proceeded to sequence the ∼371-kb contiguous locus in L er-0 using the Illumina Genome Analyzer II platform.
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