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The presence of multiple influences could potentially make RT-related activation difficult to detect if general trade-offs exist (e.g., if an increase in amplitude is precisely offset by a decrease in duration, it would be difficult to detect a difference in the resulting HDRs at short durations; Figure 1D).
However, this is precisely offset by the penalty on non-specific binding, k0, which achieves the opposite.
There is a ∼50 60% increase in quantal size that is precisely offset by a ∼30% decrease in presynaptic vesicle release (quantal content, Figure 1).
As previously shown (Daniels et al., 2004), a decrease in presynaptic release is able to precisely offset the increase in mEPSP amplitude, thereby restoring EPSP amplitudes to wild type levels.
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If so, can the expression of PHP and PHD be coordinated to produce an accurate homeostatic response, precisely offsetting the magnitude of the perturbation?
Mathematically speaking, the rate by which the per-sample f1, A decreases precisely offsets the favorable rate of increasing sample size, whereby P v does not asymptotically vanish.
Since EPSP amplitudes are maintained at wild type levels, these data support the conclusion that a homeostatic signaling system detects the change in average mEPSP amplitude and drives a compensatory reduction in presynaptic neurotransmitter release that precisely offsets the magnitude of increased mEPSP amplitude.
"Once the dust settles, leaders will be keen to demonstrate the UK's continued role in the world, precisely to offset the notion of a post-Brexit decline in power".
Hence, banks had a big incentive to save on costly equity and circumvent capital requirements which had been introduced precisely to offset such risk-taking behavior by putting assets into off-balance sheet vehicles.
It's this ability to offset precisely drawn objects with the bustling unpredictability of human life that makes Scharf's work so engaging.
7 12–14 16 Questions used to elicit transient neurological symptoms in the CFAS are likely to have captured greater numbers of transient neurological events in the population compared with those seeking more specific vascular symptoms, or to the few studies defining more precisely the onset, offset and timing of the event.
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