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The architecture of the WT FNR active site precisely contributes to reduce the stacking probability between the isoalloxazine and nicotinamide rings in the catalytically competent complex, modulating the angle and distance between the N5 of the FAD isoalloxazine and the C4 of the coenzyme nicotinamide to values that ensure efficient HT processes.
However, how each subunit precisely contributes to the progress and maintenance of cancer is largely unknown [3], [5].
How Erk precisely contributes to the regulation of the target genes was not determined.
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From a realist perspective, this goal is approached by developing an initial rough theory about how an intervention is expected to work – that is, by identifying the underlying mechanisms that are expected to cause (or more precisely contribute to) change.
As Cloé Pitiot, curator of the Pompidou retrospective points out in the catalog, it is impossible to identify precisely who contributed what to E 1027, but Gray undoubtedly used it as a forum for experimentation.
You don't want your responses to seem canned, but you do need to be prepared to say what precisely you contributed to the effort how "I" fits into "we".
The purpose of this article is precisely to contribute to a qualitative description of the public health dimension of the resource curse, taking oil extraction in sub-Saharan Africa as case in point.
Moreover, the precisely orchestrated EndMT contributes to bleomycin- and radiation-induced pulmonary fibrosis (Hashimoto et al., 2010; Choi et al., 2015).
O'Brien is critical of the limitations of the puppet cast, arguing that the recurring absence of female characters makes Unwin and Harding members of an "all-male club" and that the one regular character of the opposite sex, Mrs Appleby, "contributes precisely nil to the plot".
Precisely how this contributes to increased weight gain remains to be determined.
Usually in animal breeding, this condition is met, because a parent contributes precisely half the genes of an offspring.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com