41 Study designs involving randomisation, which could help to determine quality improvement programme effects more precisely, are challenged by ethical considerations when best practice is already well established, and practical considerations of isolating intervention from controls.
While estimating this heritability in PGx precisely is challenging (as family studies are not always readily available), the proposed heritability of most PGx traits exceeds that which has been explained so far.
But precisely because Kesha challenged double standards by seizing male rock's license to misbehave, she became a lightning rod for contempt.
Political analysts say Mr. Ouattara, a technocrat, was chosen for the position precisely because his challenged nationality meant he posed no threat to the undivided power of the country's ruler.
Judge Sarah Waters described Hall's story as "a deeply disturbing read, at once seductive and challenging – challenging, in part, precisely because it's so seductive".
Of course, the strange, and also paradoxical, thing is that it would be precisely the architecture Brandi challenged that would close it.
These stories are important precisely because they're challenged; the more unheard perspectives are released by publishers, shared by gatekeepers and connected with readers, the less they'll seem like dangerous anomalies to the people doing the challenging.
The psychiatric patient as comedian is so unexpected precisely because it challenges preconceptions.
It will involve a big battle precisely because it challenges real power.
The fleshy truth, it would seem, is that the business world's great challenges are challenging precisely because they're complex in ways that individual technological solutions cannot adequately address.
