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For myeloid progenitors to complete monocytic differentiation a complex network of intracellular signals has to be activated and/or inactivated in a precise temporal and spatial pattern.
Thus, the efficient replication of the genome, which depends on a precise temporal and spatial pattern of activation of origins of replication, is greatly impaired.
The rational design of synthetic gene delivery and expression systems continues to be essential to enable the precise temporal and spatial control of transgene expression in vivo.
It provides solid quantitative information on several aspects to support decision making, including precise temporal and spatial travel demand analysis, transfer pattern analysis, traffic condition investigation and bus utilisation analysis.
The formation of the distinct subcomponents of the CCS occurs within a precise temporal and spatial framework; thereby assuring that as the system matures from a tubular to a complex chambered organ, a rhythmic heartbeat is always maintained.
Regulatory regions of such genes can be used to express anti-pathogen effector molecules in engineered vectors in a precise temporal and spatial manner, designed to maximally affect a pathogen.
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This technique is based on computer-aided visual detection of a panel of functional biomarker measurements providing precise temporal, spatial, and contextual information that define the biological status of the cells or organs and structure of small organisms (e.g., early life stages in zebrafish).
These elements determine the precise patterns of temporal and spatial gene expression.
The orchestration of various biological processes with high fidelity requires a precise control over temporal and spatial expression of genes.
We propose an expanded gene regulatory network that contributes to the precise regulation of temporal and spatial events during early anther development.
Therefore, we exploited the RNA-seq data to assess a far more precise measurement of the temporal and spatial expression profiles of these lineage-specific genes.
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