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The 3K genomes can serve as training materials to generate accurate TALE-based algorithm prediction and more precise TALE engineering.
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These systems have been used to target integrated/synthetic as well as endogenous loci, a distinction that is reviewed by de Groote et al. [ 1].> The function of ATF was the primary purpose for DNA sequence specificity of designer ZFs and TALEs with the goal of precise transcriptional activation, also known as transactivation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com