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Although of unknown function, the LG4 locus may be a necessary cofactor required by a PPR or another mitochondrial sorting gene involved in nuclear-mitochondrial crosstalk, but again a precise regulator has not been identified.
Similarly, purinergic signalling is intimately involved in the activation of the peripheral immune response being not only a stimulator but also a precise regulator of the differentiation and function of immunocompetent cells, as well as in driving chemotaxis of neutrophiles, eosinophiles, macrophages and mast cells.
Similar(58)
In contrast, for the majority of the parameter space in the environment-driven noise regime, signal-to-noise levels of 1 or less are preferred, that is, unless regulation is very precise, noisy regulators are typically preferred over precise regulators.
While evidence is mounting supporting a role for the kinin system in ovulation, the precise regulators of this system in the ovary remains unclear.
The precise regulators of these endocytic routes are incompletely understood, but likely include actin, cholesterol, Pincher, phosphoinositide 3-kinase (PI3K) and Rac1 [ 19].
Thus, chronic alcohol exposure disrupts the delicate and precise regulation of inflammatory regulators.
Finally, p53 is an important tumor suppressor gene that acts as a transcriptional regulator of several genes essential for the precise regulation of cell division.
By characterizing the precise network regulators of a cancer type, further elucidating the nuanced differences between subtypes and further between patients, a targeting motif can be developed.
Precise interaction among regulators within assemblies can control the outcomes of specific transcripts (e.g., half-life stability and the ability to be translated).
Although adiponectin has been suggested to be one of the regulators of angiogenesis, its precise role in regulating this process is still not clear.
However, the precise role of this regulator and nitrate/nitrite respiration in the nitrogen stress response in M. smegmatis requires further investigation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com