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A precise compartmentalization of [Ca2+]i signals together with its relatively long duration and high amplitude (∼100 ms and ∼10 μ m; Sabatini et al., 2002) could result in hippocalcin translocation.
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Microfluidic droplet emulsion technology [ 7, 8] is emerging as a powerful facilitator for cellular and metabolic engineering, as various devices enable precise single-cell compartmentalization [ 9], culturing [ 10], phenotyping [ 11], and sorting [ 12].
New lines of investigation may help us understand the precise mechanisms of RER sub-compartmentalization.
The appearance of these compartments in the protoeukaryote would have marked a key step in the evolution of the eukaryotic cell, resulting in the compartmentalization of diverse biochemical processes and precise control over membrane dynamics between the organelles and with the plasma membrane (Cavalier-Smith 2002).
However, in most cases precise boundaries are formed between different cell types without early compartmentalization.
One needs to do this with some caution as the precise 'potency' of a given miRNA, as well as subcellular compartmentalization, ensures that such a calculation is unlikely to be a simple linear one.
The biosynthesis of nucleotide-sugars is catalyzed by a multitude of enzymes that reside in different subcellular organelles, and precise representation of these pathways requires accurate capture of this biological compartmentalization.
Using precise sequential transections through the pons to medulla, it was observed that there was compartmentalization of distinct rhythmogenic mechanisms in the ponto-medullary respiratory network, which has rostro-caudal organization.
Focus on compartmentalization.
Compartmentalization of digestion.
Martin, W. Evolutionary origins of metabolic compartmentalization in eukaryotes.
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