Sentence examples for precise alterations from inspiring English sources
But there is no effective way of making precise alterations in human DNA.
It will take more research to determine which precise alterations lead to autism or other neurological problems, they say.
The clustered, regularly interspaced, short palindromic repeat (CRISPR and CRISPRR associated protein 9 (Casystemstem discovered as an adaptive immunity mechanism in prokaryotes has emerged as the most popular tool for the precise alterations of the genomes of diverse species.
In our study we have related precise alterations in the way cis-regulatory information is accessed to the GC level of the genome context.
Genome engineering technologies permit precise alterations of eukaryotic genomes thereby enabling more directed and more nuanced studies of gene function.
Results: We propose SegAnnDB, a Web-based computer vision system for genomic segmentation: first, visually inspect the profiles and manually annotate altered regions, then SegAnnDB determines the precise alteration locations using a mathematical model of the data and annotations.
We selected the Rosetta compendium of deletion mutants [23] as it measures the steady state response to a very precise alteration, the deletion of a given gene, and consequently is relatively simple to associate a phenotype to a particular pathway profile.
Direct screening allows precise genome alterations that minimize the footprint of DNA alterations, such as inserted selectable markers, at the target locus.
Despite its close phylogenetic relationship with Saccharomyces cerevisiae, generating precise genomic alterations in this species is problematic.
Next, we provide a series of technical procedures for using iCRISPR to achieve one-step knockout of one or multiple gene(s), "scarless" introduction of precise nucleotide alterations, as well as inducible knockout during hPSC differentiation.
Cigarette smoking is responsible for about 90% of lung cancers and decreases survival,[1] and yet the precise molecular alterations induced by smoking in lung that develop into cancer and impact survival have remained obscure.
