By contrast, when a genetic test reveals the precise genetic abnormality causing the condition in one member of the family, it becomes simple to test other family members.
As knowledge regarding precise genetic abnormalities underlying a variety of dermatological conditions continues to emerge, the ability to introduce corresponding alterations in endogenous gene loci in mice, often at a single base pair level, has become essential for detailed studies of these genetic diseases.
We don't yet know yet what precise brain abnormalities lead to heautoscopy.
The uncertain incidence of ongoing brain injury during antiretroviral treatment, indicates a need for a more biologically-based and precise definition of abnormality also in HIV-associated neurocognitive disorders.
In the era of PET/CT, the better differentiation of physiological FDG uptake from pathological accumulations, the improved attenuation-correction and reconstruction algorithms, and the more precise localisation of abnormalities, are likely to more accurately define appropriate further investigation strategies, or to allow definitive treatment selection.
The precise tracking of an abnormality in the gastrointestinal tract is useful for medical training purposes.
Rational choice of an appropriate treatment for many of these disorders depends on determining the precise cause for the abnormality.
Precise timing of chromosomal abnormalities provides a wonderfully detailed glimpse of the etiology of a single tumor.
Furthermore, CMR provides images with high spatial resolution, free of geometric constraints, as well as precise volumetric quantification of abnormalities and direct anatomical correlation (Figs. 5, 6).
Chromosomal abnormalities with precise boundaries can be important tools to map developmental regulatory landscapes, and can be achieved with high efficiency and versatility using designer nucleases (Liu et al., 2013; Piganeau et al., 2013; Xiao et al., 2013).
