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The original Maillard hypothesis on the formation of AGEs proposed that chemical modification of proteins by reducing sugars (glycation of proteins) in diabetes alters the structure and function of tissue proteins, precipitating the development of diabetic complications (Fig. 1) [ 7].
Androgens play a vital role in men's reproductive biology, initiating the process of sexual differentiation, supporting spermatogenesis, precipitating the development of secondary sexual characteristics, and maintaining sexual function in adulthood (Bribiescas 2001a; Krause 2006).
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It is precisely this sort of issues that precipitated the development of notions such as the mind-continuum (citta-santana) and receptacle consciousness (ālaya-vijñāna).
Not surprisingly, the introduction of cell phones has helped precipitate the development of a nascent Third Industrial Revolution infrastructure.
The rise of Adolf Hitler in Nazi Germany precipitated the development of a modern armaments industry on the orders of the Soviet government.
Conditions that prevent or precipitate the development of symptomatic arteriosclerosis evolve with time and may also be different in various regions of the world [4], [9].
These risk factors may increase the incidence or precipitate the development of ARF associated with a specific disease [ 44].
Mg deficiency may thus precipitate the development of atherosclerosis and the induction of thrombocyte aggregation (Saris et al. 2000).
Post-traumatic stress disorder may precipitate the development of FM, and both conditions share similar pathogenic mechanisms [ 38].
A growing use of PCI has precipitated the development of specific guidelines by the American Heart Association AHAaimedmed at improving mortality rates and overall patient outcomes [ 13].
β-Cell exhaustion can induce failure of this compensation cycle, resulting in a deviation from NGT that precipitates the development of IGR and T2D.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com