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An NI3C C-cap mutant carrying five additional mutations in the interface to the preceding repeat, previously designed by using the consensus sequence as a guide, showed a rigid-body movement of the C-cap towards the internal repeat.
Consistent with previously reported MBT repeat structures, each MBT repeat contains an extended "arm" which packs against a globular β subunit core of the preceding repeat [1].
Two patients, who had a long disease history and severe submucosal fibrosis due to preceding repeat balloon dilation, experienced post-procedural bleeding, which resolved with conservative management.
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In this agonal state each contact stimulation of the NPh mucosa elicited AspR-es, which were even stronger than the preceding repeated gasps and resulted in cardio-respiratory resuscitation[ 19].
Furthermore, the reduced levels of H3K79Me2, another mark of transcription elongation, found upstream of the repeat in patient cells [ 51], further strengthens the idea that there is reduced transcription in the region preceding the repeat.
For each simulation iteration, the preceding was repeated n times each in the control and treatment groups, respectively, and two-sided t-tests were used to test for equality of means at α = 0.05 level of significance.
Furthermore, the hydrogen bonding and β-sheet patterns explain why HANS motifs are only found preceding Ylhead repeats [3].
Parker's rhetorical approach echoed that of Senator Bernie Sanders, the independent Vermont senator who had appeared on the programme in the preceding interview to repeat his message against the "same old, same old" procession of politics in Washington.
The expansions frequently repeat preceding measures or consist of rests or left-hand figurations without the melody, providing a pause in the motion.
To facilitate a structural comparison, the ARM repeats in human p115GHR have been renumbered such that ARM1 of Striegl et al. [13] is now labeled ARM2, and the last repeat preceding the ARM-like USO element is ARM11 (Figure 2a).
A cytoplasmic, N-terminal segment (amino acids 14 117) preceding the ankyrin repeat domain of NOMPC was expressed as a GST fusion protein and used to generate two rabbit antisera.
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