Sentence examples for preceding aggregation from inspiring English sources

IBs are the terminal stage of a series of aggregation steps, leading us to predict that IB morphology, lethality, and formation kinetics may reflect the preceding aggregation processes.

As in transgenic mice the specific pattern of Tau phosphorylation precedes aggregation, human neuronal cell lines were analyzed for Tau aggregation.

Interestingly, some thioflavin S fluorescence was observed in the supernatants after high speed ultracentrifugation (data not shown) suggesting that thioflavin S fluorescence and tau folding intermediates precede aggregation, as previously described [21].

The observation that the propensity of Aβ4 42 and AβpE3 42 to form aggregates is more pronounced than that of the N-terminally intact Aβ1 42 peptide suggests that Aβ4 42 and AβpE3 42 aggregation may precede Aβ1 42 aggregation in vivo.

The observation that the propensity of Aβ4-42 to form aggregates is more pronounced than the N-terminally intact Aβ1-42 peptide suggests that Aβ4-42 aggregation may precede Aβ1-42 aggregatinn in the in vivo condition.

Distal alpha-synuclein deposition might induce retrograde axonal degeneration, a notion which is supported by the observation that alpha-synuclein aggregates in cardiac autonomic nerves are more abundant in the distal part of the nerve and precede aggregation in the corresponding sympathetic ganglia [ 41].

Interestingly, these authors also showed that β-sheet formation precedes spontaneous aggregation, indicating that it is critical for initiation of protein polymerization.

Interestingly, these events all preceded the aggregation of the mutant SOD protein [ 49].

PLCγ2 tyrosine phosphorylation and calcium release precede both aggregation and α-granule secretion in collagen-stimulated (GPVI) signaling.

Abnormal phosphorylation of tau is considered to be one of the earliest events in neuronal degeneration and appears to precede tau aggregation.

Our results suggest that LBAS spreads retrogradely through the primary sensory neurons and preganglionic sympathetic nerves, which is plausible because the axonal development of LBAS precedes perikaryal aggregation [ 35– 35].